How to remove a hard disk from a VM

Hi

I have installed a Windows server 2003 x64 Virtual Machine and gave it 4 x hard disks:

     C:\ System

          D:\Data

               E:\More Data

                    F:\Backup of data

Now I dont need to use the F:\Backup of data so I want to remove it both from VMware and from Windows.

How can do this in a safe way?

Thanks, Maelito